Talk to your doctor of your symptoms and they can recommend appropriate treatment options like therapy, medication, or a combination of both. Practice good sleep, avoid caffeine and electronics before bedtime and establish a regular sleep routine, this can help improve insomnia symptoms.

Surgery is often recommended as a first-line treatment for brain tumors, but may not be the best option for everyone, especially for older adults who may have a higher risk of complications. Consult with a neurologist to discuss the best treatment options for your grandmother's specific case.

It sounds like he experienced a severe head injury at a young age, resulting in significant impairments. Given the complexity of your brother's situation, it would be best to seek the expertise of specialists such as pediatric neurologists or neurosurgeons, 

Stroke care often requires a multidisciplinary approach with a team of specialists to provide comprehensive treatment. Visit your doctor and get a proper course of treatment to avoid future complications.